Circulating Levels of Urokinase-Type Plasminogen Activator Receptor (uPAR) and D-Dimer in Patients with Hematological Malignancies

Conclusions We found differences in D-Dimer serum levels and soluble uPAR between controls and patients with lymphoma. These results should be considered as a biomarkers of response and survival in patients with lymphoma. Teaser This study aims to estimate sera levels of uPAR and D-D as fibrinolysis markers and to determine their association with outcome. We found an increased frequency of positive D-D. Highest sera levels of both D-D and soluble uPAR were detects for lymphoma patients against controls. These biomarkers should be related in our population with treatment response and survival.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research