Bone remodelling markers in hypertensive patients with and without diabetes mellitus: link between bone and glucose metabolism

ConclusionsIn the present study, bone formation marker, P1NP, was significantly lower in diabetic hypertensive subjects as compared with nondiabetic subjects with and without hypertension. P1NP was inversely associated with parameters of glucose homeostasis such as fasting glucose, HbA1c and positively with homeostasis model assessment‐beta cell function. Type 2 DM was associated with an adverse effect on bone formation independently of age, sex and exposure to anti‐diabetic drugs. Copyright © 2015 John Wiley & Sons, Ltd.
Source: Diabetes/Metabolism Research and Reviews - Category: Endocrinology Authors: Tags: Research Article Source Type: research