Strategies of DNA vaccines against toxoplasmosis

In humans, toxoplasmosis is widespread and can lead to serious disease, especially in pregnant women and also in immunodeficient individuals. The drugs for treatment of this disease have some toxic effects. Hence, the development to either new anti-Toxoplasma drugs or an effective vaccine would be valuable for human medicine. DNA vaccination is one of the most successful strategies for the development of a new generation of effective vaccines against intracellular parasites such as Toxoplasma gondii. This review explains the application of these strategies to improve DNA vaccine efficacy against toxoplasmosis.
Source: Reviews in Medical Microbiology - Category: Microbiology Tags: Parasitology Source Type: research