Association of the immediate perioperative dynamics of circulating DNA levels and neutrophil extracellular traps formation in cancer patients

CONCLUSION: Taken as a whole, our work reveals the association of NETs formation with the elevated cir-nDNA release during a cancer patient's perioperative period, depending on surgical procedure or cancer type. By contrast, cir-mtDNA is poorly associated with NETs formation in the studied perioperative period, which would appear to indicate a different mechanism of release or suggest mitochondrial dysfunction.PMID:38699382 | PMC:PMC11062027 | DOI:10.1093/pcmedi/pbae008
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research