Calcitonin gene ‑related peptide alleviates hyperoxia‑induced human alveolar cell injury via the CGRPR/TRPV1/Ca2 < sup > + < /sup > axis

In conclusion, exogenous CGRP acted by inversely regulating the function of TRPV1 channels in alveolar cells. Importantly, CGRP protected alveolar cells from hyperoxia‑induced injury via the CGRPR/TRPV1/Ca2+ axis, which may be a potential target for the prevention and treatment of the HILI.PMID:38695251 | DOI:10.3892/mmr.2024.13234
Source: Molecular Medicine Reports - Category: Molecular Biology Authors: Source Type: research