PELI1 overexpression contributes to pancreatic cancer progression through upregulating ubiquitination-mediated INPP5J degradation

In conclusion, the results suggest that INPP5J, decreased by PELI1 through ubiquitination, may promote PC progression. The PELI1-INPP5J axis represents a potential therapeutic targetable node for PC.PMID:38685520 | DOI:10.1016/j.cellsig.2024.111194

Source: Cellular Signalling - April 30, 2024 Category: Cytology Authors: Wenyang Zhou Xin Deng Liling Liu Yifeng Yuan Xiangpeng Meng Jia Ma Source Type: research