Optimization of Phloretin-loaded Nanospanlastics for Targeting of FAS/SREBP1c/AMPK/ OB-Rb Signaling Pathway in HFD-induced Obesity

CONCLUSIONS: Administration of PTN-NSLs significantly attenuated the levels of glycemic, oxidative stress, and inflammatory biomarkers. The biochemical and PCR findings are aided by histological investigations. Also, the present findings imply that PTN-NSLs might be a promising pharmacological tool for the treatment of obesity-related diseases.PMID:38698746 | DOI:10.2174/0113892010278684240105115516

Source: Current Pharmaceutical Biotechnology - May 3, 2024 Category: Biotechnology Authors: Mohamed Alamir Mohammed Abdalla Hussein Heba M Aboud Mohamed H Khedr Mohamed I Zanaty Source Type: research