Risk Phenotypes, Comorbidities, Pharmacotherapy, and Electroconvulsive Therapy (ECT) in a Cohort with Difficult-to-Treat Depression in Comparison to an Unmedicated Control Group

Conclusion Patients with DTD appear to experience comorbid neurotic stress
and somatoform disorders (ICD-10: F40 – F48) more frequently. Therefore, a
comprehensive differential diagnosis is crucial when patients do not respond
sufficiently to antidepressant medication. Genotyping CYP2D6 and
CYP2C19 should be considered. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text

Source: Pharmacopsychiatry - May 2, 2024 Category: Psychiatry Authors: Maier, Hannah B. Borchert, Anton Neyazi, Alexandra Moschny, Nicole Sch ülke, Rasmus Bundies, Gabriel L. Folsche, Thorsten Gaspert, Anastasia Seifert, Johanna Bleich, Stefan Scherf-Clavel, Maike Unterecker, Stefan Deckert, J ürgen Frieling, Helge Weber, Tags: Original Paper Source Type: research