First-in-Human Safety, Imaging, and Dosimetry of a Carbonic Anhydrase IX-Targeting Peptide, [68Ga]Ga-DPI-4452, in Patients with Clear Cell Renal Cell Carcinoma

Conclusion: [68Ga]Ga-DPI-4452 showed exceptional tumor uptake in patients with clear cell renal cell carcinoma, with very high tumor-to-background ratios and no significant adverse events, suggesting potential diagnostic and patient selection applications.

Source: Journal of Nuclear Medicine - May 1, 2024 Category: Nuclear Medicine Authors: Hofman, M. S., Tran, B., Feldman, D. R., Pokorska-Bocci, A., Pichereau, S., Wessen, J., Haskali, M. B., Sparks, R. B., Vlasyuk, O., Galetic, I. Tags: FEATURED ARTICLE OF THE MONTH Source Type: research