Development of a Weight-Band Dosing Approach for Vosoritide in Children with Achondroplasia Using a Population Pharmacokinetic Model

ConclusionsThe weight-band dosing regimen reduced the number of recommended dose levels by body weight and is expected to simplify dosing for children with achondroplasia and their caregivers.Clinical Trial RegistrationNCT02055157, NCT02724228, NCT03197766, NCT03424018, and NCT03583697.
Source: Clinical Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research