Microvesicles from Mesenchymal Stem Cells  Overexpressing MiR-34a Ameliorate Renal Fibrosis In Vivo

Conclusion. Our study demonstrates that miR34a further enhances the effects of MSC-MV on renal fibrosis in mice through the regulation of epithelial-to-mesenchymal transition (EMT) and Notch pathway. miR-34a may be a candidate molecular therapeutic target for the treatment of renal fibrosis. DOI: 10.52547/ijkd.7673.PMID:38660698 | DOI:10.5254/s9bdqs74

Source: Iranian Journal of Kidney Diseases - April 25, 2024 Category: Urology & Nephrology Authors: Yan Wang Ping Hu Yangping Li Ruijuan Dong Juan He Source Type: research