9. Network-Based Modeling of Brain-Wide Structural Alterations in Substance Use Disorders: A Worldwide ENIGMA Study

Substance use disorders (SUD) are increasingly recognized as network disorders and associated with system-wide structural brain alterations. Though network mechanisms have been shown to guide the spatial patterning of structural alterations in neuropsychiatric conditions, their relevance in SUD remains unclear. Here, we tested whether large-scale structural alterations in SUD relate to normative connectome architecture.

Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Foivos Georgiadis, Sara Lariviere, Sophia I. Thomopoulos, Paul M. Thompson, Philipp Homan, Scott Mackey, Patricia Conrod, Hugh Garavan, Sofie Valk, Boris Bernhardt, Matthias Kirschner, ENIGMA Addiction Working Group Source Type: research