Assessment of regional and total skeletal metabolism using 18F-NaF PET/CT in patients with chronic kidney disease

ConclusionsThe assessment of total skeleton and regional metabolism and bone turnover in CKD patients is feasible with Na[18F]F PET. Na[18F]F can help to detect early changes in bone metabolism and assess the progression of bone disease in this complex condition. Quantification with Na[18F]F PET might provide better assessment of the bone turnover. The difference in Na[18F]F uptake in CKD compared to controls is likely related to a change in bone turnover which, however, requires further validation.
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research