Molecules, Vol. 29, Pages 2003: HPLC-Based Metabolomic Analysis and Characterization of Amaranthus cruentus Leaf and Inflorescence Extracts for Their Antidiabetic and Antihypertensive Potential
Molecules, Vol. 29, Pages 2003: HPLC-Based Metabolomic Analysis and Characterization of Amaranthus cruentus Leaf and Inflorescence Extracts for Their Antidiabetic and Antihypertensive Potential
Molecules doi: 10.3390/molecules29092003
Authors:
Jesús Alfredo Araujo-León
Ivonne Sánchez-del Pino
Rolffy Ortiz-Andrade
Sergio Hidalgo-Figueroa
Areli Carrera-Lanestosa
Ligia Guadalupe Brito-Argáez
Avel González-Sánchez
Germán Giácoman-Vallejos
Oswaldo Hernández-Abreu
Sergio R. Peraza-Sánchez
Andrés Xingú-López
Víctor Aguilar-Hernández
The aim of this study was to investigate the potential of Amaranthus cruentus flavonoids (quercetin, kaempferol, catechin, hesperetin, naringenin, hesperidin, and naringin), cinnamic acid derivatives (p-coumaric acid, ferulic acid, and caffeic acid), and benzoic acids (vanillic acid and 4-hydroxybenzoic acid) as antioxidants, antidiabetic, and antihypertensive agents. An analytical method for simultaneous quantification of flavonoids, cinnamic acid derivatives, and benzoic acids for metabolomic analysis of leaves and inflorescences from A. cruentus was developed with HPLC-UV-DAD. Evaluation of linearity, limit of detection, limit of quantitation, precision, and recovery was used to validate the analytical method developed. Maximum total flavonoids contents (5.2 mg/g of lyophilized material) and cinnamic acid derivatives contents (0.6 mg/g of lyophilized material) were found in leaves. Using UV-Vis spectrophoto...
Source: Molecules - Category: Chemistry Authors: Jes ús Alfredo Araujo-León Ivonne S ánchez-del Pino Rolffy Ortiz-Andrade Sergio Hidalgo-Figueroa Areli Carrera-Lanestosa Ligia Guadalupe Brito-Arg áez Avel Gonz ález-Sánchez Germ án Giácoman-Vallejos Oswaldo Hern ández-Abreu Sergio R. Peraza-S á Tags: Article Source Type: research