Molecules, Vol. 29, Pages 2010: Systematic Review of Chemical Compounds with Immunomodulatory Action Isolated from African Medicinal Plants

Molecules, Vol. 29, Pages 2010: Systematic Review of Chemical Compounds with Immunomodulatory Action Isolated from African Medicinal Plants Molecules doi: 10.3390/molecules29092010 Authors: Wendwaoga Arsène Nikiema Moussa Ouédraogo Windbedma Prisca Ouédraogo Souleymane Fofana Boris Honoré Amadou Ouédraogo Talwendpanga Edwige Delma Belem Amadé Gambo Moustapha Abdoulaye Aimé Serge Sawadogo Raogo Ouédraogo Rasmané Semde A robust, well-functioning immune system is the cornerstone of good health. Various factors may influence the immune system’s effectiveness, potentially leading to immune system failure. This review aims to provide an overview of the structure and action of immunomodulators isolated from African medicinal plants. The research was conducted according to PRISMA guidelines. Full-text access research articles published in English up to December 2023, including plant characteristics, isolated phytochemicals, and immuno-modulatory activities, were screened. The chemical structures of the isolated compounds were generated using ChemDraw® (version 12.0.1076), and convergent and distinctive signaling pathways were highlighted. These phytochemicals with demonstrated immunostimulatory activity include alkaloids (berberine, piperine, magnoflorine), polysaccharides (pectin, glucan, acemannan, CALB-4, GMP90-1), glycosides (syringin, cordifolioside, tinocordiside, aucubin), phenolic compounds (ferulic acid, vanillic...
Source: Molecules - Category: Chemistry Authors: Tags: Systematic Review Source Type: research