Equalizing transcallosal inhibition in the mouse anterior cingulate mitigates visuospatial neglect

Trends Neurosci. 2024 Apr 23:S0166-2236(24)00060-2. doi: 10.1016/j.tins.2024.04.002. Online ahead of print.ABSTRACTA recent study by Wang and colleagues disentangled a transcallosal inhibitory circuit in mouse anterior cingulate cortex (ACC), which modulates excitatory ipsilateral tonus and contralateral inhibition by exciting contralateral parvalbumin-positive (PV+) interneurons. The authors conclude that the identified circuit mediates interhemispheric balance for visuospatial attention and provides top-down modulation of visual cortices.PMID:38658244 | DOI:10.1016/j.tins.2024.04.002
Source: Trends in Neurosciences - Category: Neuroscience Authors: Source Type: research