An EEG Signature of MCH Neuron Activities Predicts Cocaine Seeking

Identifying biomarkers that predict substance use disorder (SUD) propensity may better strategize anti-addiction treatment. The melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus (LH) critically mediates interactions between sleep and substance use; however, their activities are largely obscured in surface electroencephalogram (EEG) measures, hindering the development of biomarkers.

Source: Biological Psychiatry - April 25, 2024 Category: Psychiatry Authors: Yao Wang, Danyang Li, Joseph Widjaja, Rong Guo, Li Cai, Rongzhen Yan, Sahin Ozsoy, Giancarlo Allocca, Jidong Fang, Yan Dong, George C. Tseng, Chengcheng Huang, Yanhua H. Huang Tags: Archival Report Source Type: research