Perioperative Cefazolin for Total Joint Arthroplasty Patients Who Have a Penicillin Allergy: Is it Safe?

Cefazolin is the standard of care for perioperative antibiotic prophylaxis in total joint arthroplasty (TJA) in the United States. The potential allergic cross-reactivity between cefazolin and penicillin causes uncertainty regarding optimal antibiotic choice in patients who have a reported penicillin allergy (rPCNA). The purpose of this study was to determine the safety of perioperative cefazolin in PCNA patients undergoing primary TJA.

Source: The Journal of Arthroplasty - April 25, 2024 Category: Orthopaedics Authors: Brandon R. Bukowski, Ricardo J. Torres-Ramirez, Daniel Devine, Yu-Fen Chiu, Alberto V. Carli, Daniel B. Maalouf, Enrique A. Goytizolo, Andy O. Miller, Jose A. Rodriguez Tags: 2023 AAHKS Proceedings Source Type: research