Fraction dose escalation of hypofractionated radiotherapy with concurrent chemotherapy and subsequent consolidation immunotherapy in locally advanced non-small cell lung cancer: a phase 1 study

CONCLUSIONS: Utilizing the split-course hypo-RT and hypo-boost approach, a fraction dose of 5Gy to a total dose of 60Gy, combined with concurrent chemotherapy and subsequent cICI, was well-tolerated, and yielded promising ORR and survival outcomes.PMID:38652815 | DOI:10.1158/1078-0432.CCR-23-3600

Source: Clinical Cancer Research - April 23, 2024 Category: Cancer & Oncology Authors: Rui Zhou FangJie Liu HongMei Zhang DaQuan Wang PengXin Zhang ShiYang Zheng YiMei Liu Li Chen JinYu Guo YingYi Zou Yu-Ming Rong Hui Liu Bo Qiu Source Type: research