STAT1 mediated downregulation of the tumor suppressor gene PDCD4, is driven by the atypical cadherin FAT1, in glioblastoma

This study therefore identifies STAT1 as a novel downstream mediator of FAT1, promoting pro-tumorigenic activity in GBM, by suppressing PDCD4 expression.PMID:38640981 | DOI:10.1016/j.cellsig.2024.111178

Source: Cellular Signalling - April 19, 2024 Category: Cytology Authors: Tipu Khan Mariyam Almas Nargis Malik Akansha Jalota Shaifali Sharma Sk Asif Ali Kalpana Luthra Vaishali Suri Ashish Suri Soumen Basak Pankaj Seth Kunzang Chosdol Subrata Sinha Source Type: research