Associations among environmental exposure to trace elements and biomarkers of early kidney damage in the pediatric population

Conclusions. Among the explored metals, exposure to Cu and iodine impairs renal function. In contrast, Se may manifest as a beneficial metal. Interactions of Mo-Se and Mo-Iodine seem to alter the expression of NGAL; Mo-Cu for CLU; Mo-Cu, Mo-Se, and Mo-iodine for Cys-C and a-1MG; and Mo-Cu and Mo-iodine for KIM-1; were noticed. Our study could suggest that trace element interactions were associated with early kidney damage biomarkers.PMID:38642266 | DOI:10.1007/s10534-024-00603-3

Source: Biometals - April 20, 2024 Category: Biochemistry Authors: Manolo Ortega-Romero Elodia Rojas-Lima Juan Carlos Rubio-Guti érrez Octavio Gamaliel Aztatzi-Aguilar Juana Narv áez-Morales Mariela Esparza-Garc ía Ángel Barrera-Hernández Miguel Ángel Mejia Pablo Mendez-Hern ández Mara Medeiros Olivier Christophe Source Type: research