A rational designed multi-epitope vaccine elicited robust protective efficacy against Klebsiella pneumoniae lung infection

CONCLUSIONS: These findings suggest that mHla-EpiVac is a promising vaccine candidate against K. pneumoniae, and further validate the potential of mHla as a versatile carrier protein and adjuvant for antigen design.PMID:38643540 | DOI:10.1016/j.biopha.2024.116611

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 21, 2024 Category: Drugs & Pharmacology Authors: Jingwen Liao Xiaoli Zhang Xi Zeng Zhuo Zhao Tianjun Sun Zhenping Xia Haiming Jing Yue Yuan Zhifu Chen Qiang Gou Liqun Zhao Weijun Zhang Quanming Zou Jinyong Zhang Source Type: research