A Cohort Study to Evaluate Genetic Predictors for Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS): Results from ECOG-ACRIN E1Z11

CONCLUSION: We were unable to prospectively validate candidate SNPs previously associated with AI discontinuation due to AIMSS. Future analyses will explore additional genetic markers, PRO predictors of AIMSS, and differences by race.PMID:38640040 | DOI:10.1158/1078-0432.CCR-23-2137

Source: Clinical Genitourinary Cancer - April 19, 2024 Category: Cancer & Oncology Authors: Vered Stearns Opeyemi A Jegede Victor Tsu-Shih Chang Todd C Skaar Jeffrey L Berenberg Ranveer Nand Atif Shafqat Nisha Lassi Jacobs William Luginbuhl Paul Gilman Al B Benson Judie R Goodman Gary L Buchschacher N Lynn Henry Charles L Loprinzi Patrick J Flyn Source Type: research