Experimental rat models for Hashimoto ’s thyroiditis

ConclusionTwo rat models of autoimmune thyroiditis were obtained. EAT caused in Wistar rats by immunization with rat Tg is similar to Hashimoto ’s thyroiditis. EAT induced with porcine Tg was accompanied by oxyphil cell metaplasia in the parathyroids and hypocalcemia.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research