Underlying Neural Mechanisms of Cognitive Improvement in Fronto-striatal Response Inhibition in People Living with HIV Switching Off Efavirenz: A Randomized Controlled BOLD fMRI Trial

ConclusionPotential neural mechanisms underlying cognitive improvement after discontinuing EFV in PLWH were found in subcortical functioning, with our findings suggesting that EFV ’s effect on attention and processing speed is, at least partially, mediated by reactive inhibition.Trial RegistrationClinicaltrials.gov identifier [NCT02308332].
Source: Infectious Diseases and Therapy - Category: Infectious Diseases Source Type: research