Cobrotoxin, a single peptide from snake venom, ameliorates atopic dermatitis via suppression of MK2 modulated by IgE and IL-33

ConclusionThe study suggests that CoTX has anti-allergic and anti-inflammatory effects in allergic AD. By targeting IL-33 and IgE pathways, CoTX demonstrated potential in regulating mast cell activation and inflammatory cytokine production. The observed improvements in the AD mouse model indicate CoTX as a promising candidate for further research towards developing effective and safe treatments for AD.
Source: Molecular and Cellular Toxicology - Category: Cytology Source Type: research