Jiawei Dachaihu decoction protects against mitochondrial dysfunction in atherosclerosis (AS) mice with chronic unpredictable mild stress (CUMS) via SIRT1/PGC-1alpha/TFAM/LON signaling pathway

CONCLUSION: Jiawei Dachaihu extract could alleviate AS and reduce CUMS by upregulating the SIRT1/PGC-1α signaling and promoted its crosstalk with Lon protein to maintain mitochondrial stability.PMID:38631487 | DOI:10.1016/j.jep.2024.118150

Source: Atherosclerosis - April 17, 2024 Category: Cardiology Authors: Haijiao Shi Miao Sun Shuai Wang Fanyu He Ronglai Yang Zheng Li Wei Chen Fengrong Wang Source Type: research