Radiation for inflammatory breast cancer: Updates

Int Rev Cell Mol Biol. 2024;384:25-46. doi: 10.1016/bs.ircmb.2023.10.004. Epub 2023 Oct 19.ABSTRACTInflammatory breast cancer (IBC) is a diagnosis based on a constellation of clinical features of edema (peau d'orange) of a third or more of the skin of the breast with a palpable border and a rapid onset of breast erythema. Incidence of IBC has increased over time, although it still makes up only 1-4% of all breast cancer diagnoses. Despite recent encouraging data on clinical outcomes, the published local-regional control rates remain consistently lower than the rates for non-IBC. In this review, we focus on radiotherapy, provide a framework for multi-disciplinary care for IBC, describe local-regional treatment techniques for IBC; highlight new directions in the management of patients with metastatic IBC and offer an introduction to future directions regarding the optimal treatment and management of IBC.PMID:38637098 | DOI:10.1016/bs.ircmb.2023.10.004
Source: International Review of Cell and Molecular Biology - Category: Cytology Authors: Source Type: research