Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury

CONCLUSIONS: This study posits that the combination of AST IV and Lig has the potential to reduce the SUMO-1ylation of Drp1, augment the SUMO-2/3ylation of Drp1, and thereby exert a protective effect against CIRI.PMID:38615367 | PMC:PMC11016344 | DOI:10.1111/cns.14725
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Source Type: research