Silibinin Solubilization: Combined Effect of Co-solvency and Inclusion Complex Formation

Conclusion: SLB solubility in a buffered solution supplemented by ethanol co-solvent and HP-β-CD complexing agent is a function of free drug present in the semi-aqueous media, the drug-ligand binary complex, and the drug/ligand/co-solvent ternary complex.PMID:38625641 | DOI:10.1080/03639045.2024.2343016
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Authors: Source Type: research