The respective and dependent effects of scattering and bone matrix absorption on ultrasound attenuation in cortical bone

In this study, maps were derived from scanning acoustic microscopy images of human femur cross-sections. Finite-difference time domain ultrasound scatter simulations were conducted on these maps. Pore density, diameter distribution of the pores, and nominal absorption values in the solid and fluid matrices were controlled. Ultrasound pulses with a central frequency of 8.2 MHz were propagated, both in through-transmission and backscattering configurations. From these data, the scattering, bone matrix absorption, and attenuation extinction lengths were calculated. The results demonstrated that as absorption in the solid matrix was varied, the scattering, absorption, and attenuation extinction lengths were significantly impacted. It was shown that for lower values of absorption in the solid matrix (less than 2 dB/mm), attenuation due to scattering dominates, whereas at higher values of absorption (more than 2 dB/mm), attenuation due to absorption dominates. This will impact how ultrasound attenuation and scattering parameters can be used to extract quantitative information on bone microstructure.PMID:38631364 | DOI:10.1088/1361-6560/ad3fff
Source: Physics in Medicine and Biology - Category: Physics Authors: Source Type: research