Wide use of broad-spectrum antibiotics in very low birth weight infants with spontaneous focal intestinal perforation —is it really justified?

ConclusionThe use of carbapenems as broad-spectrum antimicrobials agents might not be justified in most VLBW infants with FIP. Knowledge on the development of the neonatal gut microbiota, local resistance patterns and individual microbiological findings should be taken into consideration when implementing antimicrobial stewardship programs (ASPs).
Source: Infection - Category: Infectious Diseases Source Type: research