Klotho-mediated activation of the anti-oxidant Nrf2/ARE signal pathway affects cell apoptosis, senescence and mobility in hypoxic human trophoblasts: involvement of Klotho in the pathogenesis of preeclampsia

The anti-aging gene Klotho is implicated in the pathogenesis of preeclampsia (PE), which is a pregnancy disease characterized by hypertension and proteinuria. Oxidative stress is closely associated with the wo...

Source: Cell Division - April 17, 2024 Category: Cytology Authors: Baomei Xu, Fang Cheng and Xiaolei Xue Tags: Research Source Type: research