150 Outcomes After Curative-Intent Radiotherapy for Lung Cancer with Driver Mutations: A Retrospective Multicentre Case-Control Study

Molecular analysis is increasingly available for non-metastatic NSCLC across the UK. Whilst patients with NSCLC and driver mutations have worse outcomes following surgery, chemotherapy and immunotherapy compared to patients with ‘wildtype’ tumours, there is a dearth of outcome data in the setting of curative-intent radiotherapy. A retrospective, multicentre, case-control study was undertaken by the British Thoracic Oncology Group trainee network in order to determine if common driver mutations impact outcomes after radi otherapy.

Source: Lung Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Salman Ashraf, Madeha Khan, Nada Naguib, Robert Rulach, Katharine Welsh, Rebecca Carozzi, Ashley Horne, Amelia Payne, Mary Denholm, Georgia Stewart, Ahmed Bedair, Stephen Harrow, Corinne Faivre-Finn, Jonathan McAleese, Gerard Hanna, Allan Hackshaw, Fiona Tags: Radiotherapy Source Type: research