Reniformin A suppresses non-small cell lung cancer progression by inducing TLR4/NLRP3/caspase-1/GSDMD-dependent pyroptosis

In conclusion, we propose that RA has a significant anticancer effect in NSCLC by inducing TLR4/NLRP3/caspase-1/GSDMD-mediated pyroptosis, which may provide a potential strategy for the treatment of NSCLC.PMID:38626545 | DOI:10.1016/j.intimp.2024.112068

Source: International Immunopharmacology - April 16, 2024 Category: Allergy & Immunology Authors: Huiyu Zhu Yifei Guan Wei Wang Xinhui Liu Sijia Wang Ran Zheng Yihan Li Lei Liu Hua Huang Source Type: research