Targeting TNF- α-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach

CONCLUSION: The findings of this study suggested that TNF-α promotes the differential expression of pro-inflammatory cytokines, TTR, and RAGE via NF-kB pathways activation. Anti-inflammatory effect of apigenin impedes TNF-α mediated dysregulation or expression associated with RA pathogenesis.PMID:38626647 | DOI:10.1016/j.cyto.2024.156616

Source: Cytokine - April 16, 2024 Category: Molecular Biology Authors: None Monu Prachi Agnihotri Mohd Saquib Sagarika Biswas Source Type: research