DNA glycosylases provide antiviral defence in prokaryotes

Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07329-9A screen utilizing an environmental DNA library in Escherichia coli is used to identify Brig1, a previously unknown anti-phage defence system with homologues across distinct clades of bacteria.

Source: Nature AOP - April 17, 2024 Category: Research Authors: Amer A. Hossain Ying Z. Pigli Christian F. Baca S øren Heissel Alexis Thomas Vincent K. Libis J án Burian Joshua S. Chappie Sean F. Brady Phoebe A. Rice Luciano A. Marraffini Source Type: research