Lymphocyte Crossmatch Testing or Donor HLA-DP and -DQ Allele Typing Effectiveness in Single Cord Blood Transplantation for Patients with Anti-HLA antibodies Other Than Against HLA-A, -B, -C, and -DRB1

Graft failure or engraftment delay is a serious complication of hematopoietic stem cell transplantation and contributes to increased non-relapse mortality (NRM). The risk of graft failure is particularly higher in cord blood transplantation (CBT), due to its relatively low number of infused cells1-4.

Source: Biology of Blood and Marrow Transplantation - April 17, 2024 Category: Hematology Authors: Makoto Osada, Hisashi Yamamoto, Otoya Watanabe, Kyosuke Yamaguchi, Kosei Kageyama, Daisuke Kaji, Yuki Taya, Aya Nishida, Kazuya Ishiwata, Shinsuke Takagi, Shigeyoshi Makino, Yuki Asano-Mori, Go Yamamoto, Shuichi Taniguchi, Atsushi Wake, Naoyuki Uchida Source Type: research