miR-215-5p Plays a Key Role in Suppressing Vascular Invasion and Recurrence in Hepatocellular Carcinoma by Blocking Vasculogenic Mimicry

CONCLUSIONS: miR-215-5p expression inversely correlates with VM occurrence in HCC tissues, while ZEB2 expression shows a direct correlation. By targeting ZEB2, miR-215-5p may hinder VM in HCC tissues, helping to prevent vascular invasion and HCC recurrence. Thus, miR-215-5p emerges as a vital prognostic indicator for predicting vascular invasion and recurrence in HCC.PMID:38538524 | DOI:10.31083/j.fbe1601006

Source: Frontiers in Bioscience - Elite - March 27, 2024 Category: Biomedical Science Authors: Heng Zhang Xi Lan Liquan Cai Xunfeng Gao Feng Gao Dan Yu Jinlong Zhang Jinhui Zhang Qinwen Tai Source Type: research