Percutaneous interventions for pulmonary embolism
EuroIntervention. 2024 Apr 1;20(7):e408-e424. doi: 10.4244/EIJ-D-23-00895.ABSTRACTPulmonary embolism (PE) ranks as a leading cause of in-hospital mortality and the third most common cause of cardiovascular death. The spectrum of PE manifestations varies widely, making it difficult to determine the best treatment approach for specific patients. Conventional treatment options include anticoagulation, thrombolysis, or surgery, but emerging percutaneous interventional procedures are being investigated for their potential benefits in heterogeneous PE populations. These novel interventional techniques encompass catheter-directed thrombolysis, mechanical thrombectomy, and hybrid approaches combining different mechanisms. Furthermore, inferior vena cava filters are also available as an option for PE prevention. Such interventions may offer faster improvements in right ventricular function, as well as in pulmonary and systemic haemodynamics, in individual patients. Moreover, percutaneous treatment may be a valid alternative to traditional therapies in high bleeding risk patients and could potentially reduce the burden of mortality related to major bleeds, such as that of haemorrhagic strokes. Nevertheless, the safety and efficacy of these techniques compared to conservative therapies have not been conclusively established. This review offers a comprehensive evaluation of the current evidence for percutaneous interventions in PE and provides guidance for selecting appropriate patients ...
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Authors: Simone Finocchiaro Maria Sara Mauro Carla Rochira Marco Spagnolo Claudio Laudani Davide Landolina Placido Maria Mazzone Federica Agnello Nicola Ammirabile Denise Cristiana Faro Antonino Imbesi Giovanni Occhipinti Antonio Greco Davide Capodanno Source Type: research
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