Mutations and intron polymorphisms in voltage-gated sodium channel genes of different geographic populations of Culex pipiens pallens/Culex pipiens quinquefasciatus in China

ConclusionsCx. p. pallens andCx. p. quinquefasciatus have developed resistance to insecticides in most regions of China. The neighboring downstream introns of thevgsc gene gradually decreased to one intron with the mutation of thevgsc gene. Mutations may originate from multiple mutation events rather than from a single origin, and populations lacking mutations may be genetically isolated.Graphical Abstract
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research