Expression of HIF ‑α and their association with clinicopathological parameters in clinical renal cell carcinoma

CONCLUSION: The expression levels of the three primary HIF-α proteins were found to be higher in the nucleus than in the cytoplasm. Furthermore, the results indicated that HIF-3α and HIF-1α expression levels were significant univariate factors associated with CSS in patients with clear cell RCC. These results highlight the critical role that HIF-3α and HIF-1α play in the hypoxia pathway.PMID:38571885 | PMC:PMC10989218 | DOI:10.48101/ujms.v129.9407
Source: Upsala Journal of Medical Sciences - Category: General Medicine Authors: Source Type: research