Interferon- α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis

ConclusionsThis study provides mechanistic evidence that IFN- α stimulates DHX58 to promote the translation of m6A-modifiedGpx4 mRNA, suggesting the potential clinical application of IFN- α in the prevention of hepatic ferroptosis during liver I/R injury.
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research