Decreased HMGCS1 inhibits proliferation and inflammatory response of keratinocytes and ameliorates imiquimod-induced psoriasis via the STAT3/IL-23 axis

In conclusion, HMGCS1 downregulation improved psoriasis in vitro and in vivo through the STAT3/IL-23 axis.PMID:38608446 | DOI:10.1016/j.intimp.2024.112033

Source: International Immunopharmacology - April 12, 2024 Category: Allergy & Immunology Authors: Lin Chen Danqi Huang Zhongzhou Huang Xiuting Liu Mingjie He Minqing Luo Zengqi Tang Guozhen Tan Qing Guo Hui Xiong Source Type: research