Differences in nature killer cell response and interference with mitochondrial DNA induced apoptosis in moxifloxacin environment

CONCLUSION: NK cells exhibit heightened sensitivity to the MXF environment. Different NK subsets upregulate the expression of cytokines and chemokines through different activation pathways. Concurrently, MXF induces impairment of the mitochondrial oxidative phosphorylation system, culminating in apoptosis.PMID:38608472 | DOI:10.1016/j.intimp.2024.111970

Source: International Immunopharmacology - April 12, 2024 Category: Allergy & Immunology Authors: Mengqing Wang Hao Wu Weiwei Jiang Yunfei Ren Xiaowei Yuan Yanan Wang Jian Zhou Wei Feng Yusen Wang Tianpeng Xu Danying Zhang Yunhao Fang Chao He Wenfang Li Source Type: research