Metabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers associated with treatment response of neoadjuvant therapy with TCbHP regimen in HER2  + breast cancer

CONCLUSION: Serum-metabolomics could be used as a powerful tool for exploring informative biomarkers for predicting or monitoring treatment efficacy. Metabolomics integrated with transcriptomics analysis could assist in obtaining new insights into biochemical pathophysiology and might facilitate the development of new treatment targets for insensitive patients.PMID:38610016 | DOI:10.1186/s13058-024-01813-w

Source: Cell Research - April 12, 2024 Category: Cytology Authors: Ningning Zhang Yuxin Huang Guanwen Wang Yimei Xiang Zhouhong Jing Junjie Zeng Feng Yu Xianjun Pan Wenqi Zhou Xiaohua Zeng Source Type: research