STAT activation in regulatory CD4+ T cells of patients with primary sclerosing cholangitis

ConclusionsIn PSC, we observed enhanced STAT3 responsiveness of CD4+ Tregs together with reduced CD39 expression probably reflecting inflammatory activity of the disease.

Source: Immunity, Inflammation and Disease - April 12, 2024 Category: Allergy & Immunology Authors: Leona Dold, Sandra Kalthoff, Leonie Frank, Taotao Zhou, Pia Esser, Philipp Lutz, Christian P. Strassburg, Ulrich Spengler, Bettina Langhans Tags: ORIGINAL ARTICLE Source Type: research