Typical antibiotic resistance genes and their association with driving factors in the coastal areas of Yangtze River Estuary
In this study, surface water samples were collected at eight sampling sites along the Yangtze River Estuary. The seasonal and spatial distribution patterns of 10 antibiotics and target genes in two major classes (sulfonamides and tetracyclines) were analyzed. The findings indicated a high prevalence of sulfonamide and tetracycline resistance genes along the Yangtze River Estuary. Kruskal-Wallis analysis revealed significant seasonal variations in the abundance of all target genes. The accumulation of antibiotic resistance genes in the coastal area of the Yangtze River Estuary can be attributed to the influence of urban instream runoff and the discharge of effluents from wastewater treatment plants. ANISOM analysis indicated significant seasonal differences in the microbial community structure. VPA showed that environmental factors contribute the most to ARG variation. PLS-PM demonstrate that environmental factors and microbial communities pose direct effect to ARG variation. Analysis of driving factors influencing ARGs in this study may shed new insights into the mechanism of the maintenance and propagation of ARGs.PMID:38607491 | DOI:10.1007/s11356-024-33198-w
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Qiuhong Xu Shuguang Liu Sha Lou Junbiao Tu Xin Li Yuchen Jin Wenjun Yin Larisa Dorzhievna Radnaeva Elena Nikitina Aleksei Nikolavich Makhinov Jos é Tavares Araruna Irina Viktorovna Fedorova Source Type: research