Skin and lung fibrosis induced by bleomycin in mice: a systematic review

CONCLUSIONS: In animal studies, it is important to simultaneously evaluate lung tissues in addition to skin fibrosis induced in mice by subcutaneous BLM application, following the 3R (replacement, reduction, and refinement) principle to avoid cruelty to animals.PMID:38523580 | DOI:10.4081/reumatismo.2024.1642

Source: Reumatismo - March 25, 2024 Category: Rheumatology Authors: S G ülle A Çelik M Birlik O Y ılmaz Source Type: research