Mediator kinase module proteins, genetic alterations and expression of super-enhancer regulated genes in colorectal cancer

CONCLUSION: The Mediator kinase module is deregulated in a sub-set of colorectal cancers with differences observed in genomically defined groups. These variations may result in differences in sensitivity to targeted therapies and may have to be taken into consideration as such therapies are developed.PMID:38602606 | DOI:10.1007/s43440-024-00589-2
Source: Pharmacological Reports - Category: Drugs & Pharmacology Authors: Source Type: research